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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PBK
All Species:
34.55
Human Site:
S122
Identified Species:
58.46
UniProt:
Q96KB5
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96KB5
NP_060962.2
322
36085
S122
M
E
Y
G
G
E
K
S
L
N
D
L
I
E
E
Chimpanzee
Pan troglodytes
XP_520045
322
36011
S122
M
E
Y
G
G
E
K
S
L
N
D
L
I
E
E
Rhesus Macaque
Macaca mulatta
XP_001109768
323
36123
S122
M
E
Y
G
G
E
K
S
L
N
D
L
I
E
E
Dog
Lupus familis
XP_534564
324
36430
S122
M
E
Y
G
G
E
K
S
L
N
D
L
I
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9JJ78
330
36726
L122
E
Y
G
G
E
K
S
L
N
D
L
I
E
E
R
Rat
Rattus norvegicus
NP_001073406
337
37551
S122
M
E
Y
G
G
E
K
S
L
N
D
L
I
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508951
321
35996
S122
M
E
Y
G
G
E
K
S
L
N
D
L
I
E
E
Chicken
Gallus gallus
XP_420011
322
35395
E122
K
S
L
N
D
L
I
E
E
R
N
A
A
R
L
Frog
Xenopus laevis
NP_001088960
325
36517
S123
M
E
Y
G
G
E
K
S
L
N
D
L
I
E
E
Zebra Danio
Brachydanio rerio
Q6DHU8
339
37645
S125
M
E
F
G
G
E
Q
S
L
N
D
L
I
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_573239
398
44994
E125
S
L
G
S
I
L
E
E
R
H
D
E
D
L
G
Honey Bee
Apis mellifera
XP_623765
343
38973
D122
K
L
D
A
S
L
G
D
R
I
E
Q
K
L
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798752
344
37735
S143
S
M
E
N
G
Q
Q
S
L
M
G
M
I
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001130276
278
30401
L87
D
Y
Q
P
N
G
S
L
Y
S
L
I
H
G
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
96.5
93.5
N.A.
85.4
86.3
N.A.
83.2
73.5
70.1
64
N.A.
35.9
41.4
N.A.
46.5
Protein Similarity:
100
99.6
98.7
96.9
N.A.
92.4
91.9
N.A.
89.7
85.4
85.2
77.2
N.A.
51.2
58.8
N.A.
63.9
P-Site Identity:
100
100
100
100
N.A.
13.3
100
N.A.
100
0
100
80
N.A.
6.6
0
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
33.3
100
N.A.
100
6.6
100
100
N.A.
20
13.3
N.A.
60
Percent
Protein Identity:
N.A.
26.7
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
45.6
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
0
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
8
0
0
8
0
8
65
0
8
8
8
% D
% Glu:
8
58
8
0
8
58
8
15
8
0
8
8
8
65
50
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
15
65
65
8
8
0
0
0
8
0
0
8
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% H
% Ile:
0
0
0
0
8
0
8
0
0
8
0
15
65
0
0
% I
% Lys:
15
0
0
0
0
8
50
0
0
0
0
0
8
0
8
% K
% Leu:
0
15
8
0
0
22
0
15
65
0
15
58
0
15
8
% L
% Met:
58
8
0
0
0
0
0
0
0
8
0
8
0
0
0
% M
% Asn:
0
0
0
15
8
0
0
0
8
58
8
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
8
15
0
0
0
0
8
0
0
8
% Q
% Arg:
0
0
0
0
0
0
0
0
15
8
0
0
0
8
8
% R
% Ser:
15
8
0
8
8
0
15
65
0
8
0
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
15
50
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _